I had similar problem on oAo server. In Logitech Profiler, my profile for GPL is set to 540 deg rotation that I'm used to. But in Global profile I have 900 deg of rotation for other sims like Assetto Corsa, that lock the wheel themselves for each car.
When the server was running in practice mode, I've joined it, Logitech Profiler correctly recognized that it's GPL and locked the wheel down to 540. But as soon as the race started, wheel reverted to Global Profile with 900 degrees... and it obviously spoiled my practice race.
I've tried reducing occurance of this problem by running everything as admin (on Win 8.1) disabling (active protection) antivirus when I drive GPL, closing down every app running in the background, unticking "Allow game to change settings" (thanks for the tip Bo), setting Global Profile to 540 degrees too.
Check if Logi Profiler keeps the right profile when the race starts DD, it might help.
Edited by Mateusz Metz, 18 August 2019 - 12:06 PM.